I am using Spine on a MacBook Pro that uses the M1 chip and it works without any problems. However, there is one known issue, although the conditions under which it occurs are not sure:
https://github.com/EsotericSoftware/spine-editor/issues/651
The issue in the ticket above can certainly be reproduced in the specific Spine projects provided to us by a user, but the way to reproduce the issue from scratch has not been found out, and in fact I have never encountered the same problem. Fortunately, even if the problem does occur, there is a workaround which is described in the ticket, so in conclusion, using Spine with M1 Mac should work well.
If you have any other concerns, please do not hesitate to ask.